Signs and symptoms of heart valve disease may include abnormal sound heart murmur when a doctor is listening to the heart beating with a stethoscope chest pain abdominal swelling more common with advanced tricuspid regurgitation fatigue shortness of breath particularly when you have been very . Symptoms congenital heart valve problems severe valve narrowing can cause a condition called cyanosis in which the skin aortic stenosis aortic stenosis usually does not cause symptoms until the valve opening narrows to about one third of aortic regurgitation a patient can have . Signs and symptoms of heart valve disease depend on the severity of the damage to the valve and the exact valve involved signs and symptoms associated with heart valve disease can include rapid weight gain palpitations chest discomfort weakness dizziness shortness of breath fainting and. Heart valve disease can cause the blood flow from your heart to your body to be disrupted if your body is not getting enough oxygen this can lead to some of these typical symptoms 1 shortness of breath chest pain fatigue low energy lightheadedness feeling dizzy and or fainting difficulty when exercising